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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fc32742cfa7190cd581609c17366685c74466e6826d19127a45a85cec992964' 
  AND token = 'nYXrkG2wPriBPC2zQmUtCm3VMc7x/9YbFCX1rrSBicI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}