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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75ebfdb8e089f8dee36e0215b75583fc21d99b5785f6d38ae4f88157f6d4e651' 
  AND token = 'NiDLza7qvMVL9oAY2Yu2j0ujoAHchu9ivNakke4Qnk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}