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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '125e94e87dd0c3e4d035741d7caac9e79a1c872c89a512860b56171307b5d37b' 
  AND token = 'Ej5NcJc13Q0Vj6+/VXwG0r07JnpDP6NwtYVOpFazW1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}