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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6c6480c2e7434c8a545f7cc8f3b4b1e10b043afefd5ae4606064af3938dbe32' 
  AND token = 'OKCVits46vYuq/OUdN2i6ldxcPKbd6kXvW4cBXn6p9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}