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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ffc8dd04994eb78e058b6c6f3124309d211fa209b29ce8d0ed7efd94447b3c2' 
  AND token = 'RMD6wZWtPVPo4yeW0D34MxWj/YS9Qv9wXVqBkWtVOKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}