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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4494abdb43b5ca7bfb0680ae0c7b1a990dcc8ae6c44e82c986c42db9898cd599' 
  AND token = 'wfAF3GLtZ7JMivyqoTaFN6Q0Tz3jk9K2WYbD7cwCYxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}