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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f54d3d2da8da1b260fa5790d58184eca8ebae81792dab74c702d871939d4ea18' 
  AND token = 'TS0q84D5f3qTK+kSn6mxUDdZoknxKg5OSCfLawH1HhY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}