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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a8afd3cb05e60c6f0d486856705cf60c4f68978313c62f81d46e03f7d0d3d21' 
  AND token = 'f23WuviC3Me2pmhgCBZuGx7Yp/uc9YMsZq8Vk7D22cw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00062

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}