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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49cc2ceb690445e6306e41ffc431b16bf97d8e4cac444885daefebe0b8312f55' 
  AND token = 'KdHCXX2ZvW6BewqHeyMr0heIx3CJSfNcUVRHTdHHwr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}