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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e131bf7a3dbacdfad8d6e111902b7d27c1777481182b08bbe974d49fc5c31cd' 
  AND token = '4+uIZJBu0WOzFl7ABqwAaMd6tlDRCAlXTiCpi/4lark=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}