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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '593c3fe0dde11be36a248e22238c4b2789da9999f556d596e8d259cb280cfd2c' 
  AND token = 'ppZMuDQIAJOh9g11lkSNUmePUurhkI/rvfy9wbRAUqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}