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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e826fd737c1981b7d47d658abe7d442a870e433331fd5b99fcd37830b68a045' 
  AND token = 'a2c8jB7Elrkboi4Tphs4DJuD/RvWZn7iDJQRYopjyZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}