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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0be8361683c131097911b0090ad1eb36acbc5a8738fb94bde4e07c1739b2fc6' 
  AND token = 'MAYFFVnMJ971Swg2LD/L3ZhaHuzTuLJZXo91Y+SwVmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}