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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d1222c98840e682311e0753a37ba3ee64a7a002486210c5296ef7100273829d' 
  AND token = 'kq8l0ko+LwQJSGrmbf4XNzkBfr95NstQ2V13gA8ckqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}