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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd3f281d1f8d0da5777becdfa6852f417a7ebc8449f7305ea361b2db225d57f9' 
  AND token = 'l+nb4h9qRLeVN/XVqHyAx3DrQaTfuP5xO8mZLuyyTnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}