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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3234e5c40c8e6605ec54fbcd524a25c9c71d1bf2b80c3e8f1fc9cee042bba4b1' 
  AND token = 'qoC+whXCNE/zTh1WHnFyF0pcU1Th1jOA2ioB7poPtU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}