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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d08b4e4cefd90344b57edcf94b7c5d728673382dd4544338cc54f2f10188db0' 
  AND token = 'myrb10mp3JgZsFM3rxQwz3EB2D9s15bFg45wTgBiuVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}