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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01a320356dbbb29b9f44ecd01a4b0a263d45d1b45ca9742bd01b88758c8e0499' 
  AND token = '/BUPj2CdNLc0oskR5qB/ffQvUyZ8RmGgljY+3kYe5MM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}