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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6599e6fec8164c65971b3e8df01031d9c90a78bd7a77863c5aa88efee6f4e20' 
  AND token = 'eWYowfs0QvPWs13b7Dlys7okKBgXqrCO0HPlOPJY+7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}