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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0073761cf299c0cd21e1074c4e8f5093dc3f4034bc6f6d1e91e31cc2e8457358' 
  AND token = 'JNE2vZhpbgDNsTgS9na9dfF8BquwaOCSHdyh6LE7pzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}