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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5661051b47715a8479051b780e20f6a1a91c8675a9da6dbebbbecf293f4ca43f' 
  AND token = 'l12td9DG9dzMqT+QHTRBTe+0uVSuCyAJh98vyMy/NcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}