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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fff19941260023893d5abb7e71140904810cbffef323d4eeea1dc727a0f5494' 
  AND token = 'JL6M0BLQpmjXz+f4fpAxzFO75TrzdXnUyX1t47sScZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}