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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d256e80aeb9a37821ea0cb862d36a22533b531df94503a61ebc5a87d0e2132d' 
  AND token = 'Rj4GC4ZeLA8MwWU3vIeNtKtiH7313xrBvZYyaZwxCME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}