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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8e631489df292c0b6358bd7cef8333020e894d4c52dd67410f8bebddf362581' 
  AND token = 'hwnSixiwY4LTz/por5gI2y0p6LBmOyC2Gu7m2MduX9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}