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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78e37fe5aff017e565458bb74f358f4c8face9ae4e3b8c9d0600cf4e81051da7' 
  AND token = '+ZatmvcOUC/dDHF7vOvfPdEfUxeFHTo5f/oIS/iWnRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}