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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1db0046a30537f4690fa7fd82031c0a04ed88164ad322291e709643318c2c2a0' 
  AND token = 'rJ/00so4cC8x0RJeGGbc+sq6SFojK7i98OgPuvJsn+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}