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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0bf9c22801111b3c1dda504c58c800514a8275aa8740da435b3f405e3ee9435e' 
  AND token = 'kFPeSGLriTu5A1SkBSS/GexYMmid8aNFpSyR5Ui9Its=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}