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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fe6e894688fe65733d6ae8ad0b485487808ab0a156f8d8a089c253199053cb7' 
  AND token = 'P0YaLa56z96wRhAqCUoYHdyMA/YeVzgVtcpfomKriEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}