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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37287dd9462d3d4997255ad75b95bd1ccf7b91d2499ac9f0f38125c9f9c5025d' 
  AND token = '878B2xAmWfE91dI56/6GBJW+KE5/S8LuCC6Ygz9n0bw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}