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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb8acf693e95de61ec7d5e2126d523f8f2685ae757f183acedd57d754b556698' 
  AND token = '2R0l6Xm4lNNxtCGUdQCCUMrm+mCFe+l8sYQl6jNeHzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}