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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a4941f0e7a2a5414363dcaf8975a88aef4335b66d99a1ea2151ebcd6527d59f' 
  AND token = 'J9FqQ8e5C/s0BRSjePlOYbYlTXQjSl9d9TqcJ3MEuqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}