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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b51c8e23caf4518fcade5f9aa7a44d49a7f535288e5e3c8142d91d544258abf' 
  AND token = 'NTY6okEqjMt9M448jRg+Esyfnrqy1FxKhT41h/F8b6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}