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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '733728b4534b2270d2734246c9b21effed8b46a839ee60767e67433b8799d8d2' 
  AND token = 'bYSZHxc7z9SU3cgtmwCQMdUxnfw9NNMwXyAyrEM7WfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}