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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24274dbcb7d4a2cd573c747f3efe578a53e3b5c3900587bb08e7e55b3834b809' 
  AND token = '24VxRRXed28bL1J1RoEx8E7yMtJXEZqJTa26XSOit+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}