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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfbd2cfd9ba9c2a1d141059b0a1740f34daa7ca7a217224a7a1bfeaf306e15a0' 
  AND token = '8DDiurPL/KXIZlk1b4cYQjP15o+gE5kDN62JRHGRIs8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}