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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3a16091729097f1953c7c7758b46b369ff6ba7606a89736f76eeac88eabe2ea' 
  AND token = 'PNce0SXJjWsAxAq/JYvJDS3vNEMVTB0dPq4GQ4zI5r4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}