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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc0a40caef23ca9f6420e1b303c407ed5e2615c1cddab945e5ecd350b2559f21' 
  AND token = 'J8jylgY3slAYp2iPRGI1bdLX5KqbkBmIXBn9O4Hs9M0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}