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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eebbbd97d47938b9a24dfa9a107b797f36c9d39a1e6e849bf8940ae31e33062f' 
  AND token = 'FWIz+HLC1/rXWd0bJIMU28hAlM0wrbIxknFSeXa5CqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}