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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64d5e0463a8f9230a06adac759b77ef913c67b0f5dd7d6e548a80091b6cb7f01' 
  AND token = 'yoGMfJLEa8sOw86fLsr0PrK9S9r+VtIcBv0dQUweKic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}