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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12c7306f05191ebe9163b9f95d526de26b1c8359e2fc6ec6ddc4a3b11d6c5aa3' 
  AND token = 'KjEc5XxPiE5R7gLittOyJO0hNwAg855g6WG42Fwnxi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}