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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '150b87e6b1a327f38a0f945c8c2a9a4f528b008d7897e4a96894ca5fc174e705' 
  AND token = 'DNW/LSJIQ6/2PC0dnUUoudFuBf5015mb7n0VqR95lcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}