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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b66c38bf9f4033765cc4705ef7a58a08cb70edd2b92da54236ed1c74a313fbd' 
  AND token = 'mQUa/k6T7N2/JtteXhY8mWSYePLyx6bbSIl1a3cSYS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}