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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd49821d4e35fd918188a97e3832428d1c8eb04017aab6534116eb4b8f3c61535' 
  AND token = '7Av7yH3N8aVI9x18Nzivt+klmR2zQsjlIZy7vpmtQsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}