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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a9b1edebaa99485514e97a9eca109495ef0a91c8c065ba327cc611b1fef271b' 
  AND token = 'Mu1m4aft3qnP3z6VQJmR4BjCsdgD9hZqpHoQxyXidLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}