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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b42003b42e0d801cda365b7a9bf9f76bd26226bd312bc36286384c23e0c3425d' 
  AND token = 'Ao3a2Pn6oxRmuZaFNSEdG2F72swkhbBfGQ8ceEiPLtg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}