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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de7d3f7839b2b42724b686d2140966fbd2017d5906f2c22f739b29962566d348' 
  AND token = 'rjiu0cGk59Snfc8neNrmuT97DtIQ8fXgfWUdZnFGhL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}