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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51c0111b899c43b9c31beb3f3a97f80e93ec157033fc7f0d1793702fd35be272' 
  AND token = 'eDYbcqBC/ez6N9q8KWXY3QHka/oICS9bjCwWyxTEolo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}