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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd395134acb670bc1fb2d4c7f7fd6e0c4d496f980116c98e0a02845a1a47e341' 
  AND token = 'V5o4aP7hTL+2mkHnf2Ln6FSeSXNgkq+5ECahXQW1DqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}