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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80e015896653fd3741c37a4a89c29d8ec8c87578ced3402eb2992dabe11a68bf' 
  AND token = 'Z6uRg1oxzJHiQejsdIbHIuTx4fGUCy3I9c1K9+mNbHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}