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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8806c1a522f07b2804f36408d5d2b16aa7f80f177c74be8c11e91259e1319e2' 
  AND token = 'joawf7mFmwTZKI/4uH9iCsUTdAz9QG2ZuGPbOE4K01U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}